Origin

Developed by C.C. Little in 1921, from a mating of Miss Abby Lathrop’s stock that also gave rise to strains C57BR and C57L. Strains 6 and 10 separated about 1937. To The Jackson Laboratory in 1948 from Hall. To NIH in 1951 from The Jackson Laboratory at F32. To Charles River in 1974 from NIH.

Strain code

027

Coat color

Black

Research application

General multipurpose model, diet-induced obesity, transgenic/knockout model development, safety and efficacy testing, immunology

MHC Haplotype

H2b